Most developers are familiar with using Ctrl + Space for intellisense, or Ctrl + Tab to cycle through open windows in Visual Studio. But Visual Studio is really keyboard friendly, and you have keyboard shortcuts for pretty much any functionality that is exposed via the various menus. You can configure them according to your preferences under Tools->Options->Environment->Keyboard. Here are 10 areas that you should definitely be familiar with:
Ctrl + K, Ctrl + D: Formats the current document
Ctrl + M, Ctrl + M: Collapse/expand current element
Ctrl + M, Ctrl + O: Collapse all
Ctrl + M, Ctrl + L: Toggle all Outlining
Go to Definition
F12: Go to definition of current code element
Ctrl + .: Open Smart Tag to allow adding missing namespaces or refactoring code.
Ctrl + Q: Focus in Quick Launch text box.
Ctrl + Shift + V: Cycle through clipboard ring.
Navigate in code editor
Ctrl + ]: Navigate to matching bracket
Ctrl + –: Navigate to last cursor location
Ctrl + Shift + –: Navigate forward to cursor location
Ctrl + K, Ctrl + C: Comments selected text
Ctrl + K, Ctrl + U: Uncomments selected text
Ctrl + K, Ctrl + K: Toggle Bookmark
Ctrl + K, Ctrl + N: Go to Next Bookmark
Enter Full Screen
Shift + Alt + Enter: View Code Editor in Full Screen